Folate Binding Protein (FOLR1) (NM_016725) Human Recombinant Protein

SKU TP701238

Purified recombinant protein of Human folate receptor 1 (adult) (FOLR1), Met1-Ser234, with C-terminal His tag, secretory expressed in HEK293 cells, 50ug

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, [RC220131], encoding the region Met1-Ser234 of FOLR1
• Tag: C-HIS
• Predicted MW: 25.7 kDa
• Concentration: >0.05 µg/µL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH 7.4, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_057937
• Locus ID: 2348
• UniProt ID: P15328 A0A024R5H1
• Cytogenetics: 11q13.4
• RefSeq Size: 1104
• RefSeq ORF: 771
• Synonyms: FBP; FOLR; FRalpha; NCFTD
• Summary: The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane