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LGR5 (NM_003667) Human Recombinant Protein

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SKU
TP700187
Purified recombinant protein of Homo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), residues 447-561aa, with C-terminal Fc tag, expressed in HEK293 cells.
Size:
20 ug
  $900.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC212825, encoding the extracellular domain (His447 - Arg561) of human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5)
Tag C-Fc
Predicted MW 38 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003658
Locus ID 8549
UniProt ID O75473
Cytogenetics 12q21.1
RefSeq Size 2880
RefSeq ORF 2721
Synonyms FEX; GPR49; GPR67; GRP49; HG38
Summary The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Sep 2015
Protein Categories GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
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Other "LGR5" proteins (3)
SKU Description Size Price
LC401213 Lyophilized LGR5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401213 Transient overexpression lysate of leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) (as WB positive control) 100 ug
$665.00
TP762667 Purified recombinant protein of Human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), 22Gly-561Arg, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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