Parathyroid hormone / PTH (32-115) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 9.55 kDa (85aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by absorbance at 280nm) |
| Purity | > 90% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 2mM EDTA |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Preparation | Liquid protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Human Parathyroid Hormone (amino acids 32-115) was overexpressed in E. coli and purified to apparent homogeneity by using conventional column Chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_000306.1 |
| Locus ID | 5741 |
| UniProt ID | P01270 |
| Cytogenetics | 11p15.3 |
| Synonyms | PTH, Human Parathyroid Hormone, PTH, Parathyrin, Parathormone, Parathyroid hormone, hPTH, Parathormone |
| Summary | This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2015 |
| Protein Categories | Endocrine and metabolic diseases, Growth Factors, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
Reviews
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Resources
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Citations
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