OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Ubiquitin (1-76) Human Protein

Be the first to review this product
SKU
SA6048
Recombinant human Ubiquitin/RPS27A protein
Size:
100 ug
  $355.00
3 Weeks*
Bulk/Customize

Other products for "UBB or NM_001281716"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGG
Predicted MW 8.6 kDa (76aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by BCA assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 50mM HEPES buffer (pH 7.4) containing 150mM NaCl, 1mM DTT, 10% glycerol
Endotoxin < 1 EU per 1ug of protein (determined by LAL method)
Preparation Liquid protein
Recommended Dilution SDS-PAGE
Protein Description Ubiquitin (76 amino acid) was overexpressed in E. coli and purified by using conventional chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq CAA44911
Locus ID 7314
UniProt ID P62979
Cytogenetics 17p11.2
Synonyms Ribosomal protein S27a, Ubiquitin carboxyl extension protein 80, Small ribosomal subunit protein eS31, UBA80, UBCEP1, UBCEP80
Summary This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2013
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Parkinson's disease
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2
Sun, Lu, Wu et al
Mol Med Rep (2019) 20 (5), 4235-4243 DOI: 10.3892/mmr.2019.10668
AI Summary: OriGene's ubiquitin expression vector was used in this study to investigate the role of ubiquitin-mediated MAD2 degradation in PTEN-deficient cells, helping to elucidate the mechanism by which PTEN maintains chromosome stability.
Snippet: GenePharma Co., Ltd. The ubiquitin expression vector was purchased from OriGene Technologies, Inc. In total, 25 µl shRNA containing lentivirus (1x108 transducing U/ml) was used for transfection. Plasmids were transfected
A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury
Bradley-Whitman, Roberts, Abner et al
Brain Inj (2017)
AI Summary: OriGene's HEK293-expressed recombinant human VILIP-1 protein was used in this study to verify the specificity of antibodies for the detection of VILIP-1 in rat serum following brain injury.
Snippet: To verify the specificity of antibodies used in this study, E. coli expressed recombinant human VILIP-1 (0.1 µg;ProSpec, East Brunswick, NJ), HEK293 expressed recombinant human VILIP-1 (0.1 µg;Origene, Rockville, MD), and E. coli expressed recombinant
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products