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RXR-alpha / RXRA (111-228) Human Protein

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SKU
SA6040X
Recombinant human RXR alpha/RXRA protein
Size:
500 ug
  $830.00
3 Weeks*
Bulk/Customize

Other products for "RXRA or NM_001291920"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE
Predicted MW 13.5 kDa (119aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl, 5mM beta-Mercaptoethanol
Preparation Liquid protein
Recommended Dilution SDS-PAGE
Protein Description The DNA binding domain of RXR (111-228 aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_002948.1
Locus ID 6256
UniProt ID P19793
Cytogenetics 9q34.2
Synonyms RXRA, NR2B1, RXR-alpha, Retinoid X receptor, Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, FLJ16020, FLJ16733, MGC102720, Retinoic acid receptor RXR alpha, RXR alpha1, RXRA1
Summary Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, May 2014
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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