RXR-alpha / RXRA (111-228) Human Protein

CAT#: SA6040

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RXR-alpha / RXRA (111-228) human protein, 0.1 mg



USD 260.00


Availability*
2 Weeks

Size
    • 100 ug


Product images

Specifications

Product Data
Description RXR-alpha / RXRA (111-228) human protein, 0.1 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE
Predicted MW 13.6 kDa
Concentration 1.0 mg/ml
Purity >95% by SDS-PAGE
Buffer Presentation State: Purified
State: Liquid protein
Buffer System: 20 mM Tris-HCl pH 7.5, 0.1 M NaCl, 5 mM beta-Mercaptoethanol
Preparation Liquid protein
Protein Description The DNA binding domain of RXR (111-228 aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_001278849
Locus ID 6256
Cytogenetics 9q34.2
Synonyms NR2B1
Summary Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Adipocytokine signaling pathway, Non-small cell lung cancer, Pathways in cancer, PPAR signaling pathway, Small cell lung cancer, Thyroid cancer

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