Beta-Synuclein / SCNB (1-134) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 14.2 kDa (134aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher) |
| Concentration | 1mg/ml (determined by BCA assay) |
| Purity | > 95% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1 M NaCl,1mM MgCl2 |
| Preparation | Liquid protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Beta-synuclein (amino acids 1-134), an acidic neuronal protein of 134 amino acids, is extremely heat-resistant. Beta-synucelin also has a chaperone-like activity. Recently, beta-synuclein has been suggested to inhibit alpha-synuclein aggregation. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_001001502.1 |
| Locus ID | 6620 |
| UniProt ID | Q16143 |
| Cytogenetics | 5q35.2 |
| Synonyms | Beta-synuclein, SNCB beta-Synuclein, B-synuclein, Phosphoneuroprotein 14, PNP14, Synuclein beta |
| Summary | This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2015 |
| Protein Categories | Intracellular Proteins, Nervous system: Neurodegenerative diseases |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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