OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

CD105 / Endoglin Human Protein

Be the first to review this product
SKU
DA3523X
CD105 / Endoglin human recombinant protein, 25 µg
Size:
25 ug
  $485.00
2 Weeks*
Bulk/Customize

Other products for "ENG or NM_000118"

Specifications
Specifications
Product Data
Species Human
Expression Host Insect
Predicted MW 90 kDa
Purity > 90% by SDS-PAGE
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized without buffer and stabilizer.
Endotoxin < 0.1 ng per µg of sCD105.
Reconstitution Method The lyophilized sCD105 is soluble in water and most aqueous buffers and should be reconstituted in PBS or medium to a concentration not lower than 50µg/ml.
Preparation Lyophilized without buffer and stabilizer.
Protein Description Human Endoglin is a disulfide-linked homodimeric protein. Based on N-terminal sequence analysis, the primary structure of recombinant mature Endoglin starts at Glu 26. Endoglin has a calculated monomeric molecular mass of 61 kDa but as a result of glycosylation, migrates at approximately 75-85 kDa under reducing conditions in SDS-PAGE.
Note Centrifuge vials before opening!
Storage Store lyophilized sCD105 at -20°C.
Reconstituted should be stored in working aliquots at -20°C to -70°C.
For long term storage as a dilute solution, a carrier protein (e.g. 0.1% HSA or BSA) should be added to the vial.
Avoid repeated freeze-thaw cycles!
Stability Shelf life: One year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_000109
Locus ID 2022
UniProt ID P17813
Cytogenetics 9q34.11
Synonyms ENG, END, HHT1, ORW, ORW1
Summary This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2013
Protein Categories CD Markers, Growth Factors, Membrane Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products