KITLG / SCF Human Protein

SKU
DA3511X
KITLG / SCF human recombinant protein, 5 µg
  $300.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host Insect
Predicted MW 18.4 kDa
Purity >95% 95% by SDS-PAGE and visualised by silver stain
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized purified protein
Buffer System: PBS, pH 7.4, without stabilizer
Bioactivity Biological: Measured in a cell proliferation assay using TF 1 human erythroleukemic cells Kitamura T et al, J Cell Physiol, 1989. The ED50 for this effect is typically 1‑5 ng/ml.
Endotoxin < 0.1 ng per µg of SCF
Reconstitution Method Restore in water to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
Preparation Lyophilized purified protein
Protein Description Recombinant Human Stem Cell Factor (SCF) His-tag.
Soluble Stem Cell Factor (SCF), a 18.4kDa protein consisting of 165 amino acid residues (Glu26-Ala190) and fused to a C-terminal His-tag (6x His).
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_000890
Locus ID 4254
UniProt ID P21583
Cytogenetics 12q21.32
Synonyms KITL, Kit ligand, c-Kit ligand, Stem cell factor, Mast cell growth factor, MGF
Summary This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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