KITLG / SCF Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | Insect |
| Predicted MW | 18.4 kDa |
| Purity | >95% 95% by SDS-PAGE and visualised by silver stain |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Lyophilized purified protein Buffer System: PBS, pH 7.4, without stabilizer |
| Bioactivity | Biological: Measured in a cell proliferation assay using TF 1 human erythroleukemic cells Kitamura T et al, J Cell Physiol, 1989. The ED50 for this effect is typically 1‑5 ng/ml. |
| Endotoxin | < 0.1 ng per µg of SCF |
| Reconstitution Method | Restore in water to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C. |
| Preparation | Lyophilized purified protein |
| Protein Description | Recombinant Human Stem Cell Factor (SCF) His-tag. Soluble Stem Cell Factor (SCF), a 18.4kDa protein consisting of 165 amino acid residues (Glu26-Ala190) and fused to a C-terminal His-tag (6x His). |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_000890 |
| Locus ID | 4254 |
| UniProt ID | P21583 |
| Cytogenetics | 12q21.32 |
| Synonyms | KITL, Kit ligand, c-Kit ligand, Stem cell factor, Mast cell growth factor, MGF |
| Summary | This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| Protein Categories | Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer |
Reviews
Documents
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Resources
| Recombinant Protein Resources |
Citations
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