Herpes Simplex Virus 2 / HSV2 (Glycoprotein G) Protein
Specifications
| Product Data | |
| Expression Host | E. coli |
|---|---|
| Predicted MW | 31 kDa |
| Concentration | lot specific |
| Purity | >95% pure (10 PAGE Coomassie staining) by GS-4B Sepharose Affinity chromatography. |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Liquid purified fraction. Buffer System: 25 mM Tris-HCl, 1 mM EDTA containing 50% glycerol without preservatives. |
| Preparation | Liquid purified fraction. |
| Recommended Dilution | Suitable for use in ELISA and Western blot. |
| Protein Description | Recombinant Herpes Simplex Virus-2 (HSV-2) Glycoprotein G (gG). Contains the HSV-2 gG immunodominant regions and GST fusion partner. Immunoreactive with HSV positive sera. |
| Storage | Store the antigen (in aliquots) at -20°C. Avoid multiple freeze/thaw cycles. |
| Stability | Shelf life: six months from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| Synonyms | HHV2 |
| Summary | Herpes Simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells |
| Protein Families | Suitable for use in ELISA and Western blot. |
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