Herpes Simplex Virus 2 / HSV2 (Glycoprotein D) Protein
Specifications
| Product Data | |
| Expression Host | E. coli |
|---|---|
| Predicted MW | 40.6 kDa |
| Concentration | lot specific |
| Purity | >95% pure (10 PAGE Coomassie staining) by GS-4B Sepharose Affinity chromatography. |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Liquid purified fraction. Buffer System: 25 mM Tris-HCl, 1 mM EDTA containing 50% glycerol without preservatives. |
| Preparation | Liquid purified fraction. |
| Recommended Dilution | Suitable for use in ELISA and Western blot. |
| Protein Description | Recombinant Herpes Simplex Virus-2 (HSV-2) Glycoprotein D (gD). Contains the HSV-2 gD immunodominant regions and GST fusion partner. Immunoreactive with HSV positive sera. |
| Storage | Store the antigen (in aliquots) at -20°C. Avoid multiple freeze/thaw cycles. |
| Stability | Shelf life: six months from despatch. |
| Shipping | Dry Ice |
| Reference Data | |
| Synonyms | HHV2 |
| Summary | There are eight members of the herpes virus family that are known to cause human disease, including not only the herpes simplex viruses (HSV1 and HSV2). HSV1 and HSV2 are family Herpesviridae, subfamily Alpha herpes virinae, genus Simplexvirus. Glycoprotein D(gD) binds specifically to the herpesvirus entry mediator receptor (HVEM), thus providing a strong, fixed attachment to the host cell. These interactions bring the membrane surfaces into mutual proximity and allow for other surface glycoproteins to interact. |
| Protein Families | Suitable for use in ELISA and Western blot. |
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Resources
| Recombinant Protein Resources |
Citations
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