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Hepatitis B Surface Antigen / HBsAg (ayw) Protein

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SKU
BIN061
Hepatitis B Surface Antigen / HBsAg (ayw) recombinant protein, 0.5 mg
Size:
500 ug
  $1,750.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Expression Host S. cerevisiae
Concentration lot specific
Purity >98% pure by SDS-PAGE).
Purification is conducted from broken yeast cells by the following scheme: Clarification, Microfiltration, Ultrafiltration, Adsorption Chromatography, Ion-exchange chromatography, Ultracentrifugation and Sterile Filtration. Product is sterile filtered.
Presentation State Purified
Buffer Presentation State: Purified
State: Liquid (sterile filtered) purified protein.
Buffer System: 0.05M Phosphate, 0.2M NaCl, pH 7.2 without preservatives.
Preparation Liquid (sterile filtered) purified protein.
Recommended Dilution Tested in ELISA with anti-HBsAg antibodies.
Protein Description Recombinant Hepatitis B Surface Antigen (HBsAg), (ayw) (S region).
Recombinant HBsAg is a 24 kDa protein.
Genotype B.
Does not contain a fusion partner.
Storage Store the antigen at 2-8°C.
Stability Shelf life: six months from despatch.
Shipping Blue Ice
Reference Data
Synonyms HBV surface antigen, Hepatitis B Virus
Summary Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Protein Families Tested in ELISA with anti-HBsAg antibodies.
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Documents
Resources

file-alt Citations

Immunogenicity of Leishmania-derived hepatitis B small surface antigen particles exposing highly conserved E2 epitope of hepatitis C virus
Czarnota, Tyborowska, Peszyńska-Sularz et al
Microb Cell Fact (2016) 15, 62 DOI: 10.1186/s12934-016-0460-4
Cited by 29
AI Summary: OriGene products, specifically the Myc-DDK monoclonal antibody (Cat# TA50011-100) and anti-DDK (FLAG) antibody (Cat# TA50011), were used in this study to detect and confirm the expression of the chimeric sHBsAg proteins in immunoblot and immunogold staining experiments.
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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