PRAME / MAPE Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 10.7 kDa |
| Purity | >98% by SDS-PAGE and Silver staining |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Lyophilized protein Buffer System: 10 mM Tris, 25 mM NaP, pH 7.4 Stabilizer: None |
| Reconstitution Method | Restore in water to a concentration of 0.1 mg/ml. |
| Preparation | Lyophilized protein |
| Recommended Dilution | Positive control for Western blot analysis. Standard for ELISA. |
| Protein Description | Recombinant human PRAME fragment corresponding to amino acid sequence Met321 to Ile420. |
| Note | mRNA RefSeq: NM_006115.3 |
| Storage | Prior to reconstitution store desiccated at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_001278644 |
| Locus ID | 23532 |
| UniProt ID | P78395 |
| Cytogenetics | 22q11.22 |
| Synonyms | OPA-interacting protein 4, OIP4, OIP-4 |
| Summary | This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2014 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Positive control for Western blot analysis. Standard for ELISA. |
Reviews
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Resources
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Citations
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