MIF (1-115, GST-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | GST-Tag |
| Predicted MW | 39.2 kDa (345aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human MIF, fused to GST-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_002406 |
| Locus ID | 4282 |
| UniProt ID | P14174 |
| Cytogenetics | 22q11.23 |
| Synonyms | Macrophage migration inhibitory factor, GIF, GLIF, MMIF |
| Summary | This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. provided by RefSeq, Jul 2008 |
| Protein Categories | Allergies and autoimmune diseases, Chemokines, Cytokines, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Phenylalanine metabolism, Tyrosine metabolism |
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Citations
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