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WNT3A (19-352) Human Protein

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SKU
AR51759PU-N
Recombinant human Wnt-3a protein
Size:
500 ug 100 ug
  $1,135.00
3 Weeks*
Bulk/Customize

Other products for "WNT3A or NM_033131"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MSYPIWWSLA VGPQYSSLGS QPILCASIPG LVPKQLRFCR NYVEIMPSVA EGIKIGIQEC QHQFRGRRWN CTTVHDSLAI FGPVLDKATR ESAFVHAIAS AGVAFAVTRS CAEGTAAICG CSSRHQGSPG KGWKWGGCSE DIEFGGMVSR EFADARENRP DARSAMNRHN NEAGRQAIAS HMHLKCKCHG LSGSCEVKTC WWSQPDFRAI GDFLKDKYDS ASEMVVEKHR ESRGWVETLR PRYTYFKVPT ERDLVYYEAS PNFCEPNPET GSFGTRDRTC NVSSHGIDGC DLLCCGRGHN ARAERRREKC RCVFHWCCYV SCQECTRVYD VHTCK
Predicted MW 37.5 kDa (335aa)
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE, Denatured
Protein Description Recombinant human WNT3a protein was expressed in E.coli.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_149122.1
Locus ID 89780
UniProt ID P56704
Cytogenetics 1q42.13
Synonyms Wnt3a, Wingless-type MMTV integration site family, member 3A
Summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. provided by RefSeq, Jul 2008
Protein Categories Cytokines, Secreated Proteins
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway
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Documents
Resources

file-alt Citations

An unbiased approach to identifying tau kinases that phosphorylate tau at sites associated with Alzheimer disease
Cavallini, Brewerton, Bell et al
J. Biol. Chem. (2013) 288 (32), 23331-47 DOI: 10.1074/jbc.M113.463984
AI Summary: OriGene’s human kinase expression plasmids were used to overexpress 352 kinases in neuroblastoma cells, enabling the authors to systematically identify which kinases phosphorylate tau at Alzheimer’s disease–relevant sites.
Snippet: were reverse co-transfected with human kinases (OriGene) and 2N4R tau (1 ng/well) using FuGENE transfection reagent (Roche Applied Science) at a 6:1 ratio (FuGENE:DNA). 48 h post-transfection, cells were lysed, and AlphaScreen assays (PerkinElmer Life Sciences) were
Showing 1-1 of 1 papers.
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