EDAR (27-448, His-tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-tag |
| Predicted MW | 48.2 kDa |
| Concentration | lot specific |
| Purity | >85% by SDS - PAGE |
| Presentation State | Purified |
| Buffer | Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl (pH 8.0) containing 10% glycerol. |
| Preparation | Liquid purified protein |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_071731 |
| Locus ID | 10913 |
| UniProt ID | Q9UNE0 |
| Cytogenetics | 2q13 |
| Synonyms | Ectodysplasin-A receptor, EDA-A1 receptor, DL, ED3, ED5, ED1R, EDA3, HRM1, EDA1R, EDA-A1R, FLJ94390 |
| Summary | This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. provided by RefSeq, Jul 2008 |
| Protein Categories | Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Reviews
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Resources
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Citations
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