RNF114 (1-228, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 28.1 kDa (251aa) |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE, Denatured |
| Protein Description | Recombinant human RNF114 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_061153 |
| Locus ID | 55905 |
| UniProt ID | Q9Y508 |
| Cytogenetics | 20q13.13 |
| Synonyms | RING finger protein 114, RING finger protein 114, PSORS12, ZNF313 |
| Summary | E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
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