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MDS1 (1-169, His-Tag) Human Protein

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SKU
AR51246PU-S
Recombinant human EVI-1 protein
Size:
20 ug 100 ug
  $425.00
3 Weeks*
Bulk/Customize

Other products for "MECOM or NM_001105077"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MRSKGRA RKLATNNECV YGNYPEIPLE EMPDADGVAS TPSLNIQEPC SPATSSEAFT PKEGSPYKAP IYIPDDIPIP AEFELRESNM PGAGLGIWTK RKIEVGEKFG PYVGEQRSNL KDPSYGWEVH LPRSRRVSVH SWLYLGKRSS DVGIAFSQAD VYMPGLQCAF LS
Tag His-Tag
Predicted MW 21.1 kDa (192aa)
Concentration 0.25mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE, Denatured
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_004982.1
Locus ID 2122
UniProt ID Q03112
Cytogenetics 3q26.2
Synonyms MDS1 and EVI1 complex locus, myelodysplasia syndrome 1, ecotropic viral integration site 1, MDS1, EVI1, PRDM3, MDS1-EVI1
Summary The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. provided by RefSeq, Mar 2011
Protein Categories Cancer: Haematopoietic and Lymphoid, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Chronic myeloid leukemia, MAPK signaling pathway, Pathways in cancer
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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