POLE3 (1-147, His-Tag) Human Protein

SKU
AR50965PU-N
Recombinant human DNA polymerase epsilon 3/POLE3 protein
  $1,135.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MAERPED LNLPNAVITR IIKEALPDGV NISKEARSAI SRAASVFVLY ATSCANNFAM KGKRKTLNAS DVLSAMEEME FQRFVTPLKE ALEAYRREQK GKKEASEQKK KDKDKKTDSE EQDKSRDEDN DEDEERLEEE EQNEEEEVDN
Tag His-Tag
Predicted MW 19.2 kDa (170aa) confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_059139
Locus ID 54107
UniProt ID Q9NRF9
Cytogenetics 9q32
Synonyms DNA polymerase epsilon 3 accessory subunit (approved)/CHRAC2, Histone fold protein CHRAC17, DNA polymerase epsilon p17 subunit, Chromatin accessibility complex 17, Arsenic transactivated protein, Chromatin accessibility complex subunit 2, AsTP, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17
Summary POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.supplied by OMIM, Apr 2004
Protein Categories Intracellular Proteins
Protein Pathways Base excision repair, DNA replication, Metabolic pathways, Nucleotide excision repair, Purine metabolism, Pyrimidine metabolism
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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