POLE3 (1-147, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 19.2 kDa (170aa) confirmed by MALDI-TOF |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_059139 |
| Locus ID | 54107 |
| UniProt ID | Q9NRF9 |
| Cytogenetics | 9q32 |
| Synonyms | DNA polymerase epsilon 3 accessory subunit (approved)/CHRAC2, Histone fold protein CHRAC17, DNA polymerase epsilon p17 subunit, Chromatin accessibility complex 17, Arsenic transactivated protein, Chromatin accessibility complex subunit 2, AsTP, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17 |
| Summary | POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.supplied by OMIM, Apr 2004 |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Base excision repair, DNA replication, Metabolic pathways, Nucleotide excision repair, Purine metabolism, Pyrimidine metabolism |
Reviews
Documents
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Resources
| Recombinant Protein Resources |
Citations
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