CD42a / GPIX (17-147, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 16.8 kDa (154aa) |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE, Denatured |
| Protein Description | Recombinant human GP9 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_000165 |
| Locus ID | 2815 |
| UniProt ID | P14770 |
| Cytogenetics | 3q21.3 |
| Synonyms | Platelet glycoprotein IX, CD42a, GPIX |
| Summary | This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. provided by RefSeq, Oct 2008 |
| Protein Categories | Cardiovascular diseases, CD Markers, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
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