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PGL2 / SDHAF2 (30-166, His-Tag) Human Protein

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SKU
AR50725PU-N
Recombinant human SDHAF2 protein
Size:
500 ug 100 ug
  $1,135.00
3 Weeks*
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Other products for "SDHAF2 or NM_017841"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGSSHHHHHH SSGLVPRGSH MGSSFRRFYR GDSPTDSQKD MIEIPLPPWQ ERTDESIETK RARLLYESRK RGMLENCILL SLFAKEHLQH MTEKQLNLYD RLINEPSNDW DIYYWATEAK PAPEIFENEV MALLRDFAKN KNKEQRLRAP DLEYLFEKPR
Tag His-Tag
Predicted MW 19kDa (160aa) confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Protein Description Recombinant human SDHAF2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_060311
Locus ID 54949
UniProt ID Q9NX18
Cytogenetics 11q12.2
Synonyms Succinate dehydrogenase assembly factor 2 mitochondrial, Succinate dehydrogenase assembly factor 2, mitochondrial, C11orf79, PGL2, SDH5
Summary This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.provided by RefSeq, Jul 2010
Protein Categories Cancer: Endocrine, Intracellular Proteins
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Documents
Resources

file-alt Citations

Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) accelerates vascular remodelling via p53 and JAK2-STAT3 regulation in vascular smooth muscle cells
Han, Heo, Myung
Br J Pharmacol (2021)
Cited by 27
AI Summary: OriGene products, specifically the Rat CIAPIN1 (Cat# RR214471L4) and p53 promoter-pGL2 basic luciferase constructs, were used in this study to investigate the molecular mechanisms by which CIAPIN1 regulates vascular smooth muscle cell behavior and vascular remodeling.
Snippet: (Cat# 631253, CA, USA). Rat CIAPIN1 (Cat# RR214471L4) was obtained from Origene Technologies (Rockville, MD, USA) This article is protected by copyright. All rights reserved. were obtained from Origene Technologies. p53 promoter-pGL2 basic luciferase
Interaction of positive coactivator 4 with histone 3.3 protein is essential for transcriptional activation of the luteinizing hormone receptor gene
Zhao, Kavarthapu, Anbazhagan et al
Biochim Biophys Acta Gene Regul Mech (2018) 1861 (10), 971-981 DOI: 10.1016/j.bbagrm.2018.09.002
Cited by 5
AI Summary: In this study, OriGene's H3.3 A/B shRNA (sc-270279) was used to deplete H3.3 in MCF7 cells, demonstrating the essential role of H3.3 in chromatin accessibility and transcriptional activation of the luteinizing hormone receptor gene.
FigureFigure
Partial growth hormone insensitivity and dysregulatory immune disease associated with de novo germline activating STAT3 mutations
Gutiérrez, Scaglia, Keselman et al
Mol. Cell. Endocrinol. (2018)
AI Summary: OriGene’s pCMV6-Entry STAT3 cDNA plasmid (RC215836) was used as the template for introducing STAT3 gene variants, enabling functional analyses of mutant STAT3 in this study.
Snippet: Gene variants were introduced into a commercial plasmid (pCMV6-Entry, RC215836, Origene, Rockville, MD, USA) containing the wild-type (WT) STAT3 cDNA (NM_139,276), using the Quick Change II XL Site-Directed Mutagenesis Kit (Agilent Technologies, Santa
Showing 1-3 of 3 papers.
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