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MYD88 (1-309, His-Tag) Human Protein

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SKU
AR50718PU-S
Recombinant human MyD88 protein
Size:
100 ug 500 ug
  $455.00
3 Weeks*
Bulk/Customize

Other products for "MYD88 or NM_002468"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MRPD RAEAPGPPAM AAGGPGAGSA APVSSTSSLP LAALNMRVRR RLSLFLNVRT QVAADWTALA EEMDFEYLEI RQLETQADPT GRLLDAWQGR PGASVGRLLE LLTKLGRDDV LLELGPSIEE DCQKYILKQQ QEEAEKPLQV AAVDSSVPRT AELAGITTLD DPLGHMPERF DAFICYCPSD IQFVQEMIRQ LEQTNYRLKL CVSDRDVLPG TCVWSIASEL IEKRCRRMVV VVSDDYLQSK ECDFQTKFAL SLSPGAHQKR LIPIKYKAMK KEFPSILRFI TVCDYTNPCT KSWFWTRLAK ALSLP
Tag His-Tag
Predicted MW 38.7 kDa (345aa)
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE, Denatured
Protein Description Recombinant human MYD88 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_002459.2
Locus ID 4615
UniProt ID Q99836
Cytogenetics 3p22.2
Synonyms Myeloid differentiation primary response protein MyD88, MYD88D
Summary This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. provided by RefSeq, Feb 2010
Protein Categories Cancer: Haematopoietic and Lymphoid, Chemokines, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome
Protein Pathways Apoptosis, Toll-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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