CD352 / SLAMF6 (22-226, His-Tag) Human Protein

SKU
AR50637PU-S
Recombinant human NTB-A/SLAMF6 protein
  $455.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
QSSLTPL MVNGILGESV TLPLEFPAGE KVNFITWLFN ETSLAFIVPH ETKSPEIHVT NPKQGKRLNF TQSYSLQLSN LKMEDTGSYR AQISTKTSAK LSSYTLRILR QLRNIQVTNH SQLFQNMTCE LHLTCSVEDA DDNVSFRWEA LGNTLSSQPN LTVSWDPRIS SEQDYTCIAE NAVSNLSFSV SAQKLCEDVK IQYTDTKM
Tag His-Tag
Predicted MW 25.5 kDa (228aa)
Concentration 1mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing, 0.4M Urea, 10% glycerol
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE,Denatured
Protein Description Recombinant human SLAMF6 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_001171643
Locus ID 114836
UniProt ID Q96DU3
Cytogenetics 1q23.2-q23.3
Synonyms SLAM family member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000
Summary The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.provided by RefSeq, May 2010
Protein Categories ADC Targets, CD Markers, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
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