CD352 / SLAMF6 (22-226, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 25.5 kDa (228aa) |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing, 0.4M Urea, 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE,Denatured |
| Protein Description | Recombinant human SLAMF6 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_001171643 |
| Locus ID | 114836 |
| UniProt ID | Q96DU3 |
| Cytogenetics | 1q23.2-q23.3 |
| Synonyms | SLAM family member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000 |
| Summary | The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.provided by RefSeq, May 2010 |
| Protein Categories | ADC Targets, CD Markers, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
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