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NACA (1-215, His-Tag) Human Protein

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SKU
AR50111PU-S
Recombinant human NACA protein
Size:
100 ug
  $455.00
3 Weeks*
Bulk/Customize

Other products for "NACA or NM_001113201"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID EEPVSKAKQS RSEKKARKAM SKLGLRQVTG VTRVTIRKSK NILFVITKPD VYKSPASDTY IVFGEAKIED LSQQAQLAAA EKFKVQGEAV SNIQENTQTP TVQEESEEEE VDETGVEVKD IELVMSQANV SRAKAVRALK NNSNDIVNAI MELTM
Tag His-Tag
Predicted MW 25.5 kDa (235aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Concentration 1mg/ml (determined by absorbance at 280nm)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15M NaCl
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Protein Description Recombinant human NACA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_001106672.1
Locus ID 4666
UniProt ID Q13765
Cytogenetics 12q13.3
Synonyms Nascent polypeptide-associated complex alpha subunit, HSD48, MGC117224, NACA1
Summary This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. provided by RefSeq, Feb 2016
Protein Categories Growth Factors
Protein Families Druggable Genome, Transcription Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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