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G-CSF (31-204) Human Protein

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SKU
AR50002PU-S
Recombinant human G-CSF protein
Size:
50 ug 250 ug
  $455.00
3 Weeks*
Bulk/Customize

Other products for "CSF3 or NM_000759"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MTPLGPASSL PQSFLLKCLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
Predicted MW 18.8 kDa (175aa) confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Bioactivity Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 range ≤0.3ng/ml.
Endotoxin < 1 EU per 1ug of protein (determined by LAL method)
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE, Bioactivity
Protein Description Recombinant Human G-CSF was expressed in E.coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_757373.1
Locus ID 1440
UniProt ID P09919
Cytogenetics 17q21.1
Synonyms Granulocyte-colony stimulating factor, CSF3, GCSF, G-CSF, G-CSF, Pluripoietin, Filgrastim, Lenograstim, Granulocyte colony-stimulating factor, Granulocyte-colony stimulating factor Colony stimulating factor 3 (granulocyte), CSF 3, CSF beta, Csfg, GCSA, Granulocyte colony stimulating factor, Lenograstim, Macrophage granulocyte inducer 2, MGC45931, MGI 2
Summary This gene encodes a member of the IL-6 superfamily of cytokines. The encoded cytokine controls the production, differentiation, and function of granulocytes. Granulocytes are a type of white blood cell that are part of the innate immune response. A modified form of this protein is commonly administered to manage chemotherapy-induced neutropenia. Alternatively spliced transcript variants have been described for this gene. provided by RefSeq, May 2020
Protein Categories Cytokines, Growth Factors, Secreated Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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