AP1 complex subunit sigma-2 / AP1S2 (1-157, His-tag) Human Protein

SKU AR39026PU-L

AP1 complex subunit sigma-2 / AP1S2 (1-157, His-tag) human recombinant protein, 0.25 mg

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  MGSSHHHHHH SSGLVPRGSH MQFMLLFSRQ GKLRLQKWYV PLSDKEKKKI TRELVQTVLA RKPKMCSFLE WRDLKIVYKR YASLYFCCAI EDQDNELITL EIIHRYVELL DKYFGSVCEL DIIFNFEKAY FILDEFLLGG EVQETSKKNV LKAIEQADLL QEEAETPRSV LEEIGLT
• Tag: His-tag
• Predicted MW: 20.7 kDa
• Concentration: lot specific
• Purity: >85%
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Liquid purified protein; Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.1M NaCl, 2 mM DTT
• Preparation: Liquid purified protein
• Protein Description: Recombinant human AP1S2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice

Reference Data

• RefSeq: NP_001259000
• Locus ID: 8905
• UniProt ID: A0A5F9ZHW1
• Cytogenetics: Xp22.2
• Synonyms: DC22, Sigma-adaptin 1B, Sigma 1B Adaptin
• Summary: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]
• Protein Families: Druggable Genome
• Protein Pathways: Lysosome