SPARC / Osteonectin Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | CHO |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 43.7 kDa |
| Concentration | N/A |
| Purity | >97% by SDS-PAGE and HPLC analyses |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Lyophilized purified protein Buffer System: 10 mM Sodium Phosphate, pH 7.6 without stabilizers Endotoxin Level: < 0.1 ng/µg of protein (<1EU/µg) |
| Bioactivity | Biological: Determined by its ability to increase alkaline phosphatase activity in differentiating MC3T3 cells using a concentration of 0.5-0.7 μg/ml. |
| Reconstitution Method | Restore in water to a concentration of 0.1-1.0 mg/ml |
| Preparation | Lyophilized purified protein |
| Protein Description | Recombinant Human SPARC/Osteonectin is a glycoprotein containing 286 amino acids that migrates at an apparent MW of 43.7 kDa by SDS-PAGE analysis due to the effect of glycosylation. |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_001296372 |
| Locus ID | 6678 |
| UniProt ID | P09486 |
| Cytogenetics | 5q33.1 |
| Synonyms | ON, Basement-membrane protein 40, BM-40 |
| Summary | This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2015 |
| Protein Categories | Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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