RSPO2 Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | CHO |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 24.4 kDa |
| Purity | >95% by SDS-PAGE and HPLC |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Lyophilized purified protein Stabilizer: None |
| Bioactivity | Biological: R-Spondin-2 enhances BMP-2 mediated differentiation of MC3T3-E1 cells. |
| Preparation | Lyophilized purified protein |
| Protein Description | Recombinant Human R-Spondin-2 is a 24.4 kDa protein consisting of 212 amino acid residues. Due to glycosylation, R-Spondin-2 migrates at an apparent molecular weight of approximately 30.0 kDa by SDS PAGE analysis under reducing conditions. |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_001269792 |
| Locus ID | 340419 |
| UniProt ID | Q6UXX9 |
| Cytogenetics | 8q23.1 |
| Synonyms | R-spondin-2 |
| Summary | This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2015 |
| Protein Categories | Intracellular Proteins, Secreated Proteins |
| Protein Families | Secreted Protein |
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