Galectin-1 Human Protein

SKU
AR31162PU-N
Galectin-1 human recombinant protein, 50 µg
  $955.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD
Predicted MW 14.5 kDa
Purity >95% by SDS-PAGE and Silver staining
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized protein
Reconstitution Method 100 mM acetic acid to a concentration of 100 ng/ml. This solution can be diluted into other buffered solutions or stored at -20°C for future use.
Preparation Lyophilized protein
Protein Description Recombinant Human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_002296
Locus ID 3956
UniProt ID P09382
Cytogenetics 22q13.1
Synonyms LGALS1, Galectin1, Lectin galactoside-binding soluble 1, Beta-galactoside-binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, MAPK-activating protein PM12
Summary The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. provided by RefSeq, Jul 2008
Protein Categories Growth Factors, Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome
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Documents
Resources

file-alt Citations

Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin α6β4 and Notch1/Jagged2 signaling pathway
Hsu, Wu, Hung et al
Carcinogenesis (2013) 34 (6), 1370-81 DOI: 10.1093/carcin/bgt040
Cited by 91
AI Summary: OriGene’s pCMV-galectin-1 and pCMV-integrin β4 plasmids were used to manipulate galectin-1 and integrin β4 expression in lung cancer cells, enabling the authors to investigate their roles in tumor metastasis.
Snippet: and cultured in RPMI1640 supplemented with 10% fetal bovine serum and 1% penicillin– streptomycin (Gibco BRL, Life Technologies) (31,32). ... CAGGCAGCG-3′. Cells were transfected with pCMV, pCMV-galectin-1 plasmid or pCMV-integrin β4 plasmid (Origene, Rockville, MD
Showing 1-1 of 1 papers.
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