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CD153 / CD30L Human Protein

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SKU
AR31160PU-N
CD153 / CD30L human recombinant protein, 50 µg
Size:
50 ug
  $510.00
2 Weeks*
Bulk/Customize

Other products for "TNFSF8 or NM_001244"

Specifications
Specifications
Product Data
Species Human
Expression Host CHO
Expression cDNA Clone or AA Sequence
Protein Sequence
HHHHHHHHPS PGGSGGQRTD SIPNSPDNVP LKGGNCSEDL LCILKR APFK KSWAYLQVAK HLNKTKLSWN KDGILHGVRY QDGNLVIQFP G LYFIICQLQ FLVQCPNNSV DLKLELLINK HIKKQALVTV CESGMQT KHV YQNLSQFLLD YLQVNTTISV NVDTFQYIDT STFPLENVLS IF LYSNSD
Predicted MW 21.3 kDa
Purity >98% by SDS-PAGE & HPLC analysis
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized purified protein
Buffer System: PBS without stabilizers
Bioactivity Biological: Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors.
Reconstitution Method Restore in water to a concentration of 0.1-1.0 mg/ml.
This solution can be diluted into other aqueous buffers and stored at 4°C for one week or at –20°C for future use.
Preparation Lyophilized purified protein
Protein Description Recombinant Human soluble CD30L (sCD30L) is a 188 amino acid polypeptide corresponding to the extracellular domain, and contains an 8 residue N-terminal His-ag
Note Centrifuge vials before opening!
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_001235
Locus ID 944
UniProt ID P32971
Cytogenetics 9q32-q33.1
Synonyms TNFSF8, CD30 Ligand, CD30LG, CD30-L
Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Nov 2011
Protein Categories CD Markers, Cytokines, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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