OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

EGF Human Protein

Be the first to review this product
SKU
AR31147PU-N
EGF human recombinant protein, 0.5 mg
Size:
500 ug
  $360.00
2 Weeks*
Bulk/Customize

Other products for "EGF or NM_001178130"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MNSDSECPLS HDGYCLHDGV CMYIEALDKY ACNCVVGYIG ERCQYRDLKW WELR.
N-terminal Sequence: MNSDSECPLS
Predicted MW 6.35 kDa
Purity >95% by SDS-PAGE & silver stain
Presentation State Purified
Buffer Presentation State: Purified
State: Sterile, Lyophilized powder.
Buffer System: PBS
Preservative: None
Stabilizer: None
Bioactivity Biological: The biological activity was determined by the ability to induce EGF receptor phosphorylation in the A431 tumor cell line Soler et al, J Chromatography B, 788, 2003 and the induction of proliferation in NHDF cells (Normal Human Dermal Fibroblasts).
Reconstitution Method A quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml.
This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Preparation Sterile, Lyophilized powder.
Protein Description Recombinant Human Epidermal Growth Factor (EGF).
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_001171601
Locus ID 1950
UniProt ID P01133
Cytogenetics 4q25
Synonyms Urogastrone, Epidermal growth factor, URG, HOMG4
Summary This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. provided by RefSeq, Jan 2016
Protein Categories Cancer: Gastrointestinal, Growth Factors, Membrane Proteins
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways Bladder cancer, Cytokine-cytokine receptor interaction, Endocytosis, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

mTOR-Dependent Stimulation of IL20RA Orchestrates Immune Cell Trafficking through Lymphatic Endothelium in Patients with Crohn's Disease
Ungaro, Garlatti, Massimino et al
Cells (2019) 8 (8) DOI: 10.3390/cells8080924
AI Summary: In this study, OriGene’s GFP-tagged Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B) was used to transduce human intestinal lymphatic endothelial cells, enabling the investigation of molecular mechanisms underlying immune cell trafficking in Crohn's disease.
Snippet: Healthy and CD HILECs were transduced with lentiviral particles, produced as previously described [12,13], carrying either Green Fluorescent Protein GFP (www.addgene.org), GFP-tagged Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B, OriGene Technologies Cached
Pikachurin interaction with dystroglycan is diminished by defective O-mannosyl glycosylation in congenital muscular dystrophy models and rescued by LARGE overexpression
Hu, Li, Zhang et al
Neurosci. Lett. (2011) 489 (1), 10-5 DOI: 10.1016/j.neulet.2010.11.056
Cited by 31
AI Summary: OriGene contributed to this study by providing the pCMV6 Entry expression plasmid encoding c-Myc-tagged human pikachurin (EGFLAM), which was used to analyze pikachurin-α-dystroglycan interactions in congenital muscular dystrophy models.
Snippet: A pCMV6 Entry expression plasmid containing c-Myc-tagged cDNA encoding the human EGF-like, fibronectin type III and laminin G domains (EGFLAM), transcript variant 1, also known as pikachurin, was obtained from Origene (Rockville, MD).
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products