Dermcidin, DCD-1L Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 4818.5 Da |
| Purity | >95% by HPLC, Reverse phase high performance liquid chromatography analysis, Electrospray ionisation mass spectrometry analysis. |
| Buffer | State: Purified peptide |
| Preparation | Purified peptide |
| Protein Description | Dermcidin, DCD-1L |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: One year from despatch. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NP_001287783 |
| Locus ID | 117159 |
| UniProt ID | P81605 |
| Cytogenetics | 12q13.2 |
| Synonyms | AIDD, DSEP, Preproteolysin |
| Summary | This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Oct 2014 |
| Protein Categories | Secreated Proteins |
| Protein Families | Secreted Protein |
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