FGF basic / FGF2 Mouse Protein

CAT#: AR31056PU-N

FGF basic / FGF2 mouse recombinant protein, 10 µg


USD 164.00

2 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Species Mouse
Expression Host E. coli
Expression cDNA Clone or AA Sequence
ALPEDGGAAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHVK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTEEC FFFERLESNN YNTYRSRKYS SWYVALKRTG QYKLGSKGPG QKAILFLPMS AKS
Result by N-terminal sequencing: ALPEDGGAAF
Predicted MW 16.34 kDa
Purity >95%
Presentation Purified
Buffer Presentation State: Purified
State: Lyophilized freeze dried protein without additives.
Buffer System: PBS without stabilizers
Bioactivity Biological: The activity was determined by the stimulation of HUVE cells. The ED50 for this effect is ≤ 0.1ng/ml corresponding to a specific activity of ≥ 1 x 10e7 units/mg.
Endotoxin < 0.1ng per μg of Mouse FGF-2
Reconstitution Restore with ddH2O or 50 mM Acetic Acid at 50 μg/ml.
This solution can be diluted into other buffered solutions or stored frozen for future use.
Preparation Lyophilized freeze dried protein without additives.
Protein Description Recombinant Mouse Fibroblast Growth Factor-2.
Storage The lyophilized Mouse FGF-2, though stable at room temperature, is best stored in working aliquots at –20°C to –70°C.
Avoid repeated freeze-thaw cycles
Reference Data
RefSeq NP_032032
Locus ID 14173
UniProt ID P15655, Q541T2
Cytogenetics 3 18.41 cM
Synonyms bFGF; Fgf-2; Fgfb
Summary Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.[UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.