FGF basic / FGF2 Mouse Protein

SKU AR31056PU-N

FGF basic / FGF2 mouse recombinant protein, 10 µg

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  ALPEDGGAAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHVK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTEEC FFFERLESNN YNTYRSRKYS SWYVALKRTG QYKLGSKGPG QKAILFLPMS AKS; Result by N-terminal sequencing: ALPEDGGAAF
• Predicted MW: 16.34 kDa
• Purity: >95%
• Presentation State: Purified
• Buffer: Presentation State: Purified; State: Lyophilized freeze dried protein without additives.; Buffer System: PBS without stabilizers
• Bioactivity: Biological: The activity was determined by the stimulation of HUVE cells. The ED50 for this effect is ≤ 0.1ng/ml corresponding to a specific activity of ≥ 1 x 10e7 units/mg.
• Endotoxin: < 0.1ng per μg of Mouse FGF-2
• Reconstitution Method: Restore with ddH2O or 50 mM Acetic Acid at 50 μg/ml.; This solution can be diluted into other buffered solutions or stored frozen for future use.
• Preparation: Lyophilized freeze dried protein without additives.
• Protein Description: Recombinant Mouse Fibroblast Growth Factor-2.
• Storage: The lyophilized Mouse FGF-2, though stable at room temperature, is best stored in working aliquots at –20°C to –70°C.; Avoid repeated freeze-thaw cycles
• Shipping: Ambient

Reference Data

• RefSeq: NP_032032
• Locus ID: 14173
• UniProt ID: P15655
• Cytogenetics: 3 18.41 cM
• Synonyms: FGFB, Heparin-binding growth factor 2, Fibroblast growth factor 2 (basic), BFGF, HBGF-2, HBGF2
• Summary: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.[UniProtKB/Swiss-Prot Function]