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FGF basic / FGF2 Mouse Protein

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SKU
AR31056PU-L
FGF basic / FGF2 mouse recombinant protein, 50 µg
Size:
50 ug
  $510.00
2 Weeks*
Bulk/Customize

Other products for "Fgf2 or NM_008006"

Specifications
Specifications
Product Data
Species Mouse
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
ALPEDGGAAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHVK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTEEC FFFERLESNN YNTYRSRKYS SWYVALKRTG QYKLGSKGPG QKAILFLPMS AKS
Result by N-terminal sequencing: ALPEDGGAAF
Predicted MW 16.34 kDa
Purity >95%
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized freeze dried protein without additives.
Buffer System: PBS without stabilizers
Bioactivity Biological: The activity was determined by the stimulation of HUVE cells. The ED50 for this effect is ≤ 0.1ng/ml corresponding to a specific activity of ≥ 1 x 10e7 units/mg.
Endotoxin < 0.1ng per μg of Mouse FGF-2
Reconstitution Method Restore with ddH2O or 50 mM Acetic Acid at 50 μg/ml.
This solution can be diluted into other buffered solutions or stored frozen for future use.
Preparation Lyophilized freeze dried protein without additives.
Protein Description Recombinant Mouse Fibroblast Growth Factor-2.
Storage The lyophilized Mouse FGF-2, though stable at room temperature, is best stored in working aliquots at –20°C to –70°C.
Avoid repeated freeze-thaw cycles
Shipping Ambient
Reference Data
RefSeq NP_032032
Locus ID 14173
UniProt ID P15655
Cytogenetics 3 18.41 cM
Synonyms FGFB, Heparin-binding growth factor 2, Fibroblast growth factor 2 (basic), BFGF, HBGF-2, HBGF2
Summary Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.UniProtKB/Swiss-Prot Function
Protein Categories Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins
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Documents
Resources

file-alt Citations

Pluripotent stem cells induced from mouse neural stem cells and small intestinal epithelial cells by small molecule compounds
Ye, Ge, Zhang et al
Cell Res. (2015)
Cited by 88
AI Summary: OriGene's basic fibroblast growth factor (bFGF) was used to culture neural stem cells, enabling their maintenance and subsequent chemical reprogramming into pluripotent stem cells in this study.
Snippet: Fetal NSCs were isolated from mouse forebrain at embryonic day 13.5 as previously described41, and postnatal NSCs were isolated from the subventricular zone of the postnatal mouse brain41,42. NSCs were cultured in NSC culture medium (DMEM/F-12 (1:1), DF12) containing N2 and B27 supplements, 1% non-essential amino acids (NEAA), 2 mM GlutaMAX, 10 U PS, 55 μM β-mercaptoethanol (β-me) (all from Invitr...
Showing 1-1 of 1 papers.
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