FGF basic / FGF2 Mouse Protein
Other products for "Fgf2"
Specifications
Product Data | |
Species | Mouse |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
ALPEDGGAAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHVK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTEEC FFFERLESNN YNTYRSRKYS SWYVALKRTG QYKLGSKGPG QKAILFLPMS AKS
Result by N-terminal sequencing: ALPEDGGAAF |
Predicted MW | 16.34 kDa |
Purity | >95% |
Presentation | Purified |
Buffer | Presentation State: Purified State: Lyophilized freeze dried protein without additives. Buffer System: PBS without stabilizers |
Bioactivity | Biological: The activity was determined by the stimulation of HUVE cells. The ED50 for this effect is ≤ 0.1ng/ml corresponding to a specific activity of ≥ 1 x 10e7 units/mg. |
Endotoxin | < 0.1ng per μg of Mouse FGF-2 |
Reconstitution | Restore with ddH2O or 50 mM Acetic Acid at 50 μg/ml. This solution can be diluted into other buffered solutions or stored frozen for future use. |
Preparation | Lyophilized freeze dried protein without additives. |
Protein Description | Recombinant Mouse Fibroblast Growth Factor-2. |
Storage | The lyophilized Mouse FGF-2, though stable at room temperature, is best stored in working aliquots at –20°C to –70°C. Avoid repeated freeze-thaw cycles |
Reference Data | |
RefSeq | NP_032032 |
Locus ID | 14173 |
UniProt ID | P15655, Q541T2 |
Cytogenetics | 3 18.41 cM |
Synonyms | bFGF; Fgf-2; Fgfb |
Summary | Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis.[UniProtKB/Swiss-Prot Function] |
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