Hepatitis B Surface Antigen / HBsAg (adw) Protein
$1,725.00
2 Weeks*
Specifications
| Product Data | |
| Expression Host | Pichia pastoris |
|---|---|
| Predicted MW | 25.5 kDa |
| Concentration | lot specific |
| Purity | >95% by SDS-PAGE (Coomassie staining). Purified from broken yeast cells using clarification, microfiltration, chromatography, gel filtration, ultra filtration and sterile filtration. |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 200 mM Na2HPO4 and 30 mM Sodium Chloride, pH 9.4 without preservatives Preservative: None |
| Preparation | Liquid purified protein |
| Recommended Dilution | ELISA. Western Blot. |
| Protein Description | Recombinant Hepatitis B Surface Antigen (HBsAg) (adw) Recombinant HBsAg subtype adw. Contains full-length HBsAg (226 amino acids, MW of 25.5kDa). Genotype B |
| Note | Centrifuge before opening to ensure complete recovery of vial contents. |
| Storage | Store the antigen at 2-8°C. DO NOT FREEZE! |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| Synonyms | HBV surface antigen, Hepatitis B Virus |
| Summary | Hepatitis B Virus (HBV) infection induces a disease state characterized by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr. |
| Protein Families | ELISA. Western Blot. |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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