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Gremlin-1 / GREM1 Mouse Protein

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SKU
AR26008PU-N
Gremlin-1 / GREM1 mouse recombinant protein, 50 µg
Size:
50 ug
  $300.00
2 Weeks*
Bulk/Customize

Other products for "Grem1 or NM_011824"

Specifications
Specifications
Product Data
Species Mouse
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MKKKGSQGAI PPPDKAQHND SEQTQSPPQP GSRTRGRGQG RGTAMPGEEV LESSQEALHV TERKYLKRDW CKTQPLKQTI HEEGCNSRTI INRFCYGQCN SFYIPRHIRK EEGSFQSCSF CKPKKFTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD
Predicted MW 28 kDa
Purity >95% by SDS-PAGE & Silver staining
Presentation State Purified
Buffer Presentation State: Purified
State: Lyophilized protein
Buffer System: 50 mM acetic acid, without stabilizers
Endotoxin < 0.1 ng per μg of Grem1
Reconstitution Method Mouse Grem1 should be reconstituted in 50mM acetic acid or water to a concentration of 0.1 mg/ml. This solution can be diluted in water or other buffer solutions.
Preparation Lyophilized protein
Protein Description Recombinant mouse Gremlin-1 / GREM1, aa. 160
Note Protein RefSeq: NP_035954.1
mRNA RefSeq: NM_011824
Storage The lyophilized protein is stable at room temperature for up to 1 week or at -20 °C for longer. Following reconstitution store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Ambient
Reference Data
RefSeq NP_035954
Locus ID 23892
UniProt ID O70326
Cytogenetics 2 57.43 cM
Synonyms DAND2, CKTSF1B1, DRM, PIG2, IHG-2, GREM-1
Summary Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop (PubMed:12808456, PubMed:15201225). Down-regulates the BMP4 signaling in a dose-dependent manner (PubMed:15133038). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Cytokines, Growth Factors, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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