PTP4A1 / PRL1 (1-170, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 21.6 kDa (190aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human PTP4A1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_003454.1 |
| Locus ID | 7803 |
| UniProt ID | Q93096 |
| Cytogenetics | 6q12 |
| Synonyms | Protein tyrosine phosphatase type IVA 1, HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX17C1 |
| Summary | This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. provided by RefSeq, Jun 2013 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Phosphatase |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET
Shirasaki, Yamagoe, Shimakami et al
Nat Commun (2022) 13 (1), 3176 DOI: 10.1038/s41467-022-30879-3
Shirasaki, Yamagoe, Shimakami et al
Nat Commun (2022) 13 (1), 3176 DOI: 10.1038/s41467-022-30879-3
Cited by 18
AI Summary: OriGene contributed to this study by providing the LECT2, PTP4A1, and DC-SIGN cDNA plasmids, which were used to investigate the molecular mechanisms underlying LECT2's role in antiviral immune regulation.
Assessment of Research on Intimate Partner Violence (IPV) Among Sexual Minorities in the United States
Kim, Schmuhl
Trauma Violence Abuse (2021) 22 (4), 766-776 DOI: 10.1177/1524838019881732
Kim, Schmuhl
Trauma Violence Abuse (2021) 22 (4), 766-776 DOI: 10.1177/1524838019881732
Cited by 34
AI Summary: There is no mention of any OriGene products in the provided abstract or information about the paper "Assessment of Research on Intimate Partner Violence (IPV) Among Sexual Minorities in the United States," so OriGene products did not contribute to this study.
Enhanced PRL-1 expression in placenta-derived mesenchymal stem cells accelerates hepatic function via mitochondrial dynamics in a cirrhotic rat model
Kim, Choi, Jun et al
Stem Cell Res Ther (2020) 11 (1), 512 DOI: 10.1186/s13287-020-02029-3
Kim, Choi, Jun et al
Stem Cell Res Ther (2020) 11 (1), 512 DOI: 10.1186/s13287-020-02029-3
Cited by 18
AI Summary: In this study, OriGene’s PRL-1 cDNA clone (Cat# RC201307) and PRL-1 antibody (Cat# TA326952) were used to generate and detect PRL-1-overexpressing placenta-derived mesenchymal stem cells, enabling the researchers to evaluate the role of enhanced PRL-1 expression in improving mitochondrial and hepatic function in a cirrhotic rat model.
Dynamic Regulation of miRNA Expression by Functionally Enhanced Placental Mesenchymal Stem Cells PromotesHepatic Regeneration in a Rat Model with Bile Duct Ligation
Kim, Jun, Park et al
Int J Mol Sci (2019) 20 (21) DOI: 10.3390/ijms20215299
Kim, Jun, Park et al
Int J Mol Sci (2019) 20 (21) DOI: 10.3390/ijms20215299
Cited by 26
AI Summary: In this study, OriGene’s PRL-1 plasmid (containing the CMV6-AC vector and neomycin resistance) was used to overexpress PRL-1 in placental mesenchymal stem cells, enabling the researchers to investigate the enhanced therapeutic mechanisms of these modified cells in promoting liver regeneration.
Snippet: …Louis, MO, USA), and 1% penicillin/streptomycin (P/S;Gibco). To overexpress human PRL-1 (phosphatase of regenerating liver-1;protein tyrosine phosphatase type 4 A, member 1;PTP4A1) in naïve PD-MSCs, a PRL-1 plasmid containing the CMV6-AC vector and antibiotic neomycin for mammalswas obtained from Origene(Origene Inc., Rockville, MD, US
Showing 1-4 of 4 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
