MIP4 / CCL18 (22-89, His-Tag) Human Protein

SKU
AR09793PU-N
Recombinant human CCL18/MIP-4 protein
  $1,135.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQVGTN KELCCLVYTS WQIPQKFIVD YSETSPQCPK PGVILLTKRG RQICADPNKK WVQKYISDLK LNA
Tag His-Tag
Predicted MW 10.4 kDa (93aa) confirmed by MALDI-TOF
Concentration 0.25mg/ml (determined by BCA assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 10mM Sodium Citrate buffer (pH 3.5) containing 10% glycerol
Endotoxin < 1 EU per 1ug of protein (determined by LAL method)
Preparation Liquid purified peptide
Recommended Dilution SDS-PAGE
Protein Description Recombinant human CCL18, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_002979
Locus ID 6362
UniProt ID P55774
Cytogenetics 17q12
Synonyms C-C motif chemokine ligand 18, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, CC chemokine PARC, Dendritic cell chemokine 1, DC-CK1, Macrophage inflammatory protein 4, MIP-4, Pulmonary and activation-regulated chemokine, PARC, Small-inducible cytokine A18, SCYA18
Summary This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. provided by RefSeq, Sep 2014
Protein Categories Chemokines, Cytokines, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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