PHLDA2 / TSSC3 (1-152, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 19.2 kDa (172aa) confirmed by MALDI-TOF |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human PHLDA2 protein, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_003302.1 |
| Locus ID | 7262 |
| UniProt ID | Q53GA4 |
| Cytogenetics | 11p15.4 |
| Synonyms | Pleckstrin homology-like domain family A member 2, BRW1C, BWR1C, HLDA2, IPL, TSSC3, Pleckstrin homology-like domain family A member 2 Beckwith Wiedemann syndrome chromosome region 1 candidate protein C, BRW 1C, BWR 1C, HLDA 2, HLDA2, Imprinted in placenta and liver, Imprinted in placenta and liver protein, p17 Beckwith Wiedemann region 1C, p17 BWR1C, PHLDA 2, Pleckstrin homology like domain family A member 2, TSSC 3, Tumor supressing STF cDNA 3, Tumor suppressing STF cDNA 3 protein, Tumor suppressing subchromosomal transferable, fragment candidate gene 3 protein, Tumor suppressing subchromosomal transferable fragment cDNA 3, Tumor suppressing subtransferable candidate 3 |
| Summary | This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver. provided by RefSeq, Oct 2010 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
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