ALDH3 (1-453, His-Tag) Human Protein
$1,480.00
3 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 52.5 kDa (473aa) |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl |
| Bioactivity | Specific activity is > 5,000pmol/min/ug, and is defined as the amount of enzyme that catalyze the oxidation of 1.0 pmole 4-nitrobenzaldehyde by NADP per minute at pH 9.0 at 37℃. |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE, Enzyme Activity |
| Protein Description | Recombinant ALDH3A1 protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | AAH04370.1 |
| Locus ID | 218 |
| UniProt ID | P30838 |
| Cytogenetics | 17p11.2 |
| Synonyms | Aldehyde dehydrogenase 3 family memberA1, ALDHIII, ALDH3, Aldehyde dehydrogenase 3 family, memberA1 AHD 4.AHD C, AHD4, AHDC, ALDH III, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase 3 family member A1, Aldehyde dehydrogenase 3A1, Aldehyde dehydrogenase class 3, Aldehyde dehydrogenase dimeric NADP preferring, Aldehyde dehydrogenase family 3 member A1, Aldehyde dehydrogenase family 3 subfamily A1, Aldehyde dehydrogenase isozyme 3, Aldehyde dehydrogenase type III, ALDH 3, ALDH 3A1, ALDH3 A1, ALDH3A 1, MGC10406, Stomach aldehyde dehydrogenase, Tumor associated aldehyde dehydrogenase tumor ALDH. |
| Summary | Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. provided by RefSeq, Sep 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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