GTF2B (1-316, His-tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-tag |
| Predicted MW | 36.9 kDa |
| Concentration | lot specific |
| Purity | >90% by SDS - PAGE |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl |
| Preparation | Liquid purified protein |
| Protein Description | Recombinant GTF2B protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_001505 |
| Locus ID | 2959 |
| UniProt ID | Q00403 |
| Cytogenetics | 1p22.2 |
| Synonyms | Transcription initiation factor IIB, TF2B, TFIIB |
| Summary | This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Basal transcription factors |
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