PTGES3 / TEBP (1-160) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 18.6 kDa (160aa) confirmed by MALDI-TOF |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 95% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant PTGES3 protein (160 aa) was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_006592 |
| Locus ID | 10728 |
| UniProt ID | Q15185 |
| Cytogenetics | 12 |
| Synonyms | PTGES3, cPGES, P23, TEBP, HSP90 co-chaperone, Sid 3177, Co chaperone p23, Hsp90 co chaperone, Cytosolic prostaglandin E2 synthase, Progesterone receptor complex, Progesterone receptor complex p23, Prostaglandin E synthase 3, PTGES 3, Telomerase binding protein p23, unactive progesterone receptor 23 kD |
| Summary | This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. provided by RefSeq, Feb 2016 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor |
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