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LIN28 (42-209, His-Tag) Human Protein

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SKU
AR09295PU-N
Recombinant human LIN-28A protein
Size:
50 ug
  $570.00
3 Weeks*
Bulk/Customize

Other products for "LIN28A or NM_024674"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGSSHHHHHH SSGLVPRGSH RSMGICKWFN VRMGFGFLSM TARAGVALDP PVDVFVHQSK LHMEGFRSLK EGEAVEFTFK KSAKGLESIR VTGPGGVFCI GSERRPKGKS MQKRRSKGDR CYNCGGLDHH AKECKLPPQP KKCHFCQSIS HMVASCPLKA QQGPSAQGKP TYFREEEEEI HSPTLLPEAQ N
Tag His-Tag
Predicted MW 21.1 kDa (191aa) confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 85% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl, 0.1mM PMSF
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Protein Description Recombinant Lin28 protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_078950
Locus ID 79727
UniProt ID Q9H9Z2
Cytogenetics 1p36.11
Synonyms Zinc finger CCHC domain-containing protein 1, ZCCHC1, Tex17, RNA binding protein lin 28, LIN28A, LIN-28, Lin 28 homolog A, Lin 28 homolog, FLJ12457, CSDD1
Summary This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. provided by RefSeq, Sep 2015
Protein Categories Growth Factors, Intracellular Proteins
Protein Families et al. (2003) Dev. Biol. 258:432-442.
Heo I., et al. (2009) Cell. 138:696-708., Protocol: Moss E.G.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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