ALDH1 (1-501) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Predicted MW | 54.8 kDa (501aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 50mM Tris-HCl buffer (pH 7.5) containing 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant ALDH1A1 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_000680.2 |
| Locus ID | 216 |
| UniProt ID | P00352 |
| Cytogenetics | 9q21.13 |
| Synonyms | Aldehyde dehydrogenase 1A1, ALDC, ALDH1, PUMB1, RALDH 1, 3-deoxyglucosone dehydrogenase 1, ALDH-E1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic 1, Retinal dehydrogenase 1 |
| Summary | The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. provided by RefSeq, Mar 2011 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Metabolic pathways, Retinol metabolism |
Reviews
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Resources
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Citations
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