TARC / CCL17 (24-94, His-Tag) Human Protein

SKU
AR09248PU-N
Recombinant human CCL17/TARC protein
  $455.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MGSSHHHHHH SSGLVPRGSH MARGTNVGRE CCLEYFKGAI PLRKLKTWYQ TSEDCSRDAI VFVTVQGRAI CSDPNNKRVK NAVKYLQSLE RS
Tag His-Tag
Predicted MW 10.3 kDa (92aa) confirmed by MALDI-TOF
Concentration 0.5mg/ml (determined by Bradford assay)
Purity > 95% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Endotoxin < 1 EU per 1ug of protein (determined by LAL method)
Preparation Liquid purified peptide
Recommended Dilution SDS-PAGE
Protein Description CCL17, fused to His-tag, was expressed in E.coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_002978
Locus ID 6361
UniProt ID Q92583
Cytogenetics 16q21
Synonyms Chemokine (C-C motif) ligand 17, A-152E5.3, ABCD-2, SCYA17, TARC, Chemokine (C-C motif) ligand 17 A152E53, ABCD2, CC Chemokine TARC, CCL17, Chemokine CC Motif Ligand 17, MGC138271, MGC138273, Small Inducible Cytokine A17, Small Inducible Cytokine A17 Precursor, Small Inducible Cytokine Subfamily A (Cys Cys), Small Inducible Cytokine Subfamily A (Cys Cys) Member 17, T Cell Directed CC Chemokine, Thymus and activation regulated chemokine
Summary This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. provided by RefSeq, Sep 2014
Protein Categories Chemokines, Cytokines, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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