SAR1A (1-198, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 24.5 kDa (218aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human SAR1A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_064535 |
| Locus ID | 56681 |
| UniProt ID | Q9NR31 |
| Cytogenetics | 10q22.1 |
| Synonyms | SARA 1, Sara, SAR1a gene homolog 1 COPII associated small GTPase, SAR1a gene homolog 1 (S. cerevisiae), SAR1A, SAR1 homolog A (S. cerevisiae), SAR1 gene homolog A, SAR 1, Masra 2, GTP binding protein SAR1a, COPII-associated small GTPase |
| Summary | Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).UniProtKB/Swiss-Prot Function |
| Protein Categories | Intracellular Proteins |
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