PTX3 (18-381, His-Tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-Tag |
| Predicted MW | 44.4 kDa (401aa) confirmed by MALDI-TOF |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Presentation State | Purified |
| Buffer | Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol |
| Preparation | Liquid purified protein |
| Recommended Dilution | SDS-PAGE |
| Protein Description | Recombinant human Pentraxin 3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Storage | Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_002843.1 |
| Locus ID | 5806 |
| UniProt ID | P26022 |
| Cytogenetics | 3q25.32 |
| Synonyms | TNFAIP5, TSG-14, Pentraxin 3, AI607804, Pentaxin 3, Pentaxin-related protein PTX3, Pentraxin-related gene, rapidly induced by IL-1 beta, Pentraxin-related gene, PTX3, TSG14, Tumor necrosis factor-inducible gene 14 protein, Tumor necrosis factor-inducible protein TSG-14 |
| Summary | This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. provided by RefSeq, Jun 2016 |
| Protein Categories | Cytokines, Secreated Proteins |
| Protein Families | Secreted Protein |
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