WIF1 (29-379, His-tag) Human Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | Insect |
| Expression cDNA Clone or AA Sequence | |
| Tag | His-tag |
| Predicted MW | 40.5 kDa |
| Concentration | lot specific |
| Purity | >90% by SDS - PAGE |
| Presentation State | Purified |
| Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: PBS (pH 7.4) containing 20% glycerol, 1 mM PMSF, 1 mM DTT |
| Endotoxin | < 1.0 EU per 1 µg of protein (determined by LAL method ) |
| Preparation | Liquid purified protein |
| Protein Description | Recombinant human Wif-1 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography. |
| Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_009122 |
| Locus ID | 11197 |
| UniProt ID | Q9Y5W5 |
| Cytogenetics | 12q14.3 |
| Synonyms | WIF-1, UNQ191/PRO217 |
| Summary | The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. provided by RefSeq, Jun 2010 |
| Protein Categories | Growth Factors, Intracellular Proteins, Secreated Proteins |
| Protein Families | Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway |
| Protein Pathways | Wnt signaling pathway |
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