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Alpha-1-antitrypsin (25-418) Human Protein

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SKU
AR09121PU-N
Recombinant human Serpin A1/alpha 1-Antitrypsin protein
Size:
100 ug
  $455.00
3 Weeks*
Bulk/Customize

Other products for "SERPINA1 or NM_000295"

Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MEDPQGDAAQ KTDTSHHDQD HPTFNKITPN LAEFAFSLYR QLAHQSNSTN IFFSPVSIAT AFAMLSLGTK ADTHDEILEG LNFNLTEIPE AQIHEGFQEL LRTLNQPDSQ LQLTTGNGLF LSEGLKLVDK FLEDVKKLYH SEAFTVNFGD TEEAKKQIND YVEKGTQGKI VDLVKELDRD TVFALVNYIF FKGKWERPFE VKDTEEEDFH VDQVTTVKVP MMKRLGMFNI QHCKKLSSWV LLMKYLGNAT AIFFLPDEGK LQHLENELTH DIITKFLENE DRRSASLHLP KLSITGTYDL KSVLGQLGIT KVFSNGADLS GVTEEAPLKL SKAVHKAVLT IDEKGTEAAG AMFLEAIPMS IPPEVKFNKP FVFLMIDQNT KSPLFMGKVV NPTQK
Predicted MW 44.4 kDa (395aa) confirmed by MALDI-TOF
Concentration 1mg/ml (determined by Bradford assay)
Purity > 90% by SDS-PAGE
Presentation State Purified
Buffer Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol, 1mM DTT, 2mM EDTA
Preparation Liquid purified protein
Recommended Dilution SDS-PAGE
Protein Description Recombinant Antitrypsin protein was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80C. Avoid repeated freezing and thawing cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Reference Data
RefSeq NP_000286.2
Locus ID 5265
UniProt ID P01009
Cytogenetics 14q32.13
Synonyms PI, A1A, AAT, PI1, A1AT, MGC9222, PRO2275, MGC23330, SERP1NA1, Alpha-1 antiproteinase, Serine proteinase inhibitor, Antitrypsin, Alpha 1 antiproteinase, Alpha 1 antitrypsin, alpha 1 AT, Alpha 1 protease inhibitor, alpha1 PI, MGC23330, alpha1 proteinase inhibitor, Clade A member 1, cysteine proteinase inhibitor, Serpin A1, Protease inhibitor 1, Serpin peptidase inhibitor clade A member 1, SerpinA1, Alpha-1 Antitrypsin, A1AT, serum trypsin inhibitor
Summary The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. provided by RefSeq, Aug 2020
Protein Categories Intracellular Proteins, Secreated Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Complement and coagulation cascades
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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