Alpha-1-antitrypsin (25-418) Human Protein

CAT#: AR09121PU-N

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Alpha-1-antitrypsin (25-418) human recombinant protein, 0.1 mg


Product Datasheet for 'AR09121PU-N'


USD 330.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Description Alpha-1-antitrypsin (25-418) human recombinant protein, 0.1 mg
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence MEDPQGDAAQ KTDTSHHDQD HPTFNKITPN LAEFAFSLYR QLAHQSNSTN IFFSPVSIAT AFAMLSLGTK ADTHDEILEG LNFNLTEIPE AQIHEGFQEL LRTLNQPDSQ LQLTTGNGLF LSEGLKLVDK FLEDVKKLYH SEAFTVNFGD TEEAKKQIND YVEKGTQGKI VDLVKELDRD TVFALVNYIF FKGKWERPFE VKDTEEEDFH VDQVTTVKVP MMKRLGMFNI QHCKKLSSWV LLMKYLGNAT AIFFLPDEGK LQHLENELTH DIITKFLENE DRRSASLHLP KLSITGTYDL KSVLGQLGIT KVFSNGADLS GVTEEAPLKL SKAVHKAVLT IDEKGTEAAG AMFLEAIPMS IPPEVKFNKP FVFLMIDQNT KSPLFMGKVV NPTQK
Predicted MW 44.4 kDa
Concentration 1.0 mg/ml (determined by Bradford assay)
Purity >90% by SDS PAGE
Buffer Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris pH 7.5, 10% Glycerol, 1 mM DTT, 2 mM EDTA
Preparation Liquid purified protein
Protein Description Recombinant Antitrypsin protein was expressed in E.coli and purified by using conventional chromatography techniques.
Storage Store at 2-8°C for 1-2 weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000286
Locus ID 5265
Cytogenetics 14q32.13
Synonyms A1A; A1AT; AAT; alpha1AT; nNIF; PI; PI1; PRO2275
Summary The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Complement and coagulation cascades

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